GSHPx: A Key Enzyme in Immune System and Antioxidant Defenses

Target Name: Glutathione peroxidase

NCBI ID: P13494

Glutathione peroxidase

Other Name(s): GSHPx | GPX | GPx

GSHPx: A Key Enzyme in Immune System and Antioxidant Defenses

Glutathione peroxidase (GSHPx) is a protein that plays a crucial role in the immune system and antioxidant defenses. It is a nonspecific subtype of the antioxidant enzyme glutathione peroxidase (GPx), which is responsible for the production of glutathione, a powerful antioxidant that protects cells from damage caused by free radicals. GPx is a cytoplasmic protein that can be found in most tissues and cells of the body. It is a subunit of the superfamily of NAD+-dependent enzymes known as the NAD+-dependent oxidorespiratory chain.

GSHPx is a 23-kDa protein that is expressed in a variety of tissues and cells, including the liver, muscle, heart, kidney, and pancreas. It is primarily localized to the cytoplasm of cells and is involved in the production of glutathione, which is a highly reactive molecule that can react with a wide variety of molecules, including oxygen, nitrogen, carbon, and hydrogen. Glutathione is a powerful antioxidant that can donate electrons to other molecules, thereby reducing their oxidation and protecting cells from damage.

GSHPx is a critical enzyme in the immune system and plays a key role in the production of T cells, which are a crucial part of the immune system. T cells are responsible for cell division, immune response, and regulation of the immune system. They are produced in the bone marrow and are a part of the adaptive immune system, which is responsible for protecting the body against infection and disease. T cells are characterized by their ability to recognize and respond to foreign antigens, which are molecules that are specific to the body's tissues and cells.

GSHPx is also involved in the production of other important molecules that are involved in the immune system, including antibodies, which are proteins that are produced by the immune system in response to the presence of a foreign antigen. antibodies are able to recognize and bind to the foreign antigens, thereby neutralizing them and protecting the body against infection.

In addition to its role in the immune system, GSHPx is also involved in the production of other important molecules that are involved in cellular signaling and metabolism. For example, GSHPx is involved in the production of reactive oxygen species (ROS), which are molecules that are produced when cells respond to stress or environmental conditions. ROS are able to damage cells and contribute to a wide range of cellular processes, including cell death, DNA damage, and inflammation. GSHPx is also involved in the production of glutamyl-modified transferase (GMT), which is a protein that is involved in the metabolism of glucose and other nutrients.

GSHPx is a highly conserved protein that is found in most organisms, including humans. It is able to function in a variety of cellular contexts and is involved in a wide range of cellular processes. In addition to its role in the immune system and metabolism, GSHPx is also involved in the production of other important molecules that are involved in the regulation of cellular signaling pathways.

GSHPx is a potential drug target for a variety of diseases. For example, GSHPx has been shown to be involved in a wide range of diseases, including cancer, neurodegenerative diseases, and autoimmune diseases. In addition, GSHPx has also been shown to be involved in a variety of cellular processes that are involved in the development and progression of these diseases. For example, GSHPx has been shown to be involved in the development of neurodegenerative diseases, such as Alzheimer's disease and Parkinson's disease, which are characterized by the progressive loss of brain cells and the accumulation of neurofibrillary tangles. GSHPx has also been shown to be involved in the development of cancer,

Protein Name: Glutathione Peroxidase (nonspecified Subtype)

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•   general information;
•   protein structure and compound binding;
•   protein biological mechanisms;
•   its importance;
•   the target screening and validation;
•   expression level;
•   disease relevance;
•   drug resistance;
•   related combination drugs;
•   pharmacochemistry experiments;
•   related patent analysis;
•   advantages and risks of development, etc.
The report is helpful for project application, drug molecule design, research progress updates, publication of research papers, patent applications, etc. If you are interested to get a full version of this report, please feel free to contact us at BD@silexon.ai

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